Announcements and coverage.
- · bioRxiv Structure-free, site-resolved contrastive learning extends small-molecule discovery beyond the reach of structure-based modeling (opens in a new tab) The model paper. Ptarmigan-1 co-embeds protein residues and small molecules without predicting a pose, screening billions of compounds across the human proteome in under a day — and reaching disordered targets where co-folding falls to near-random.
- · Talus Bio Talus Bio announces collaboration with PRISM BioLab to discover novel modulators of transcription factor and protein-protein interaction targets A strategic collaboration pairing PRISM's PepMetics® chemistry with Talus's regulome profiling and AI models, against transcription factor and protein-protein interaction targets.
- · Talus Bio Regulome Summit 2025: a milestone for chromatin biology and drug discovery The inaugural Regulome Summit brought genome scientists, technologists, and AI researchers to the University of Washington to chart a path toward drugging regulome targets.
- · bioRxiv Native, Spatiotemporal Profiling of the Global Human Regulome (opens in a new tab) The platform paper. Compartment-resolved profiling across 36 human cell lines recovers 897 transcription factors — roughly 60% of the annotated human repertoire.
- · Talus Bio Talus Bio presents preclinical data on transcription factor therapeutic programs at AACR 2025
- · Talus Bio Eqvista Profiles Talus Bio CEO in its Founder Spotlight Interview Series
- · Talus Bio Talus Bio announces new VP of Business Development to accelerate pharma partnerships
- · Talus Bio Introducing Drugging the Undruggable, a new blog series from Talus Bio
- · Substack Introducing Drugging the Undruggable, a blog series from Talus Bio (opens in a new tab) The original announcement of the series. Posts now live at /blog.
- · Talus Bio Human Proteome Organization Honors Co-Founder and CTO Lindsay Pino
- · Talus Bio Talus Bio announces new Head of Biology to advance transcription factor therapeutics
- · Talus Bio Life Science Success Podcast Features COO/CFO Michelle Briscoe
- · Fierce Biotech Talus Bio tacks on $11.2M in additional funding to target hard-to-reach transcription factors (opens in a new tab) Coverage of the funding round led by Two Bear Capital.
- · Talus Bio New Funding to Advance Talus Bio’s AI Platform for Therapeutic Discovery
- · Talus Bio Fierce Biotech Features Talus Bio’s Latest Funding Round
- · Talus Bio PSBJ Recognizes Talus Bio COO Michelle Briscoe in Voices of Pride Ceremony
- · Talus Bio New Grants to Accelerate Talus Bio’s Development of Transcription Factor Drugs
- · Talus Bio The Proteomics Show with Dr. Lindsay Pino
- · Talus Bio Talus Bio Wants to Knock Proteins off DNA
- · Talus Bio Talus Announces Close of Seed Funding Round and Hires New COO
- · Talus Bio Innovating in Oncology Webinar Features Lindsay Pino
- · Talus Bio Talk is Biotech! Podcast with Guru Singh
- · Talus Bio The Lady Scientist Podcast Features Lindsay Pino, CTO
- · Talus Bio Why I Joined A Biotech Startup